![]() ![]() An increased F A/F i results in faster induction. ![]() PA (P brain) = input (delivery) – uptake (into pulmonary circulation)į i = concentration of inspired anesthetic in delivered gas flowsį A/F i = The rate of rise of concentration which determines the speed of inhalational induction.Equilibrium between alveolar partial pressures (PA) and arterial blood (Pa) results in steady-state partial pressures in the brain.Inhaled anesthetics function by achieving optimal and constant partial pressure at the CNS effect site (brain, spinal cord).The partial pressure is directly proportional to tissue concentration which determines its clinical effect.The partial pressure of a gas is the fraction of the mixture that the agent comprises.Nitrous oxide is an inhaled anesthetic that works primarily by NMDA receptor antagonism. ![]()
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